Time to See the Difference: Video Capture for Patient-Centered Clinical Trials
Authored by Aparito and Alexion, AstraZeneca Rare Disease, "Time to See the Difference: Video Capture for Patient-Centered Clinical Trials" outlines FDA and EMA approved drugs that utilised video-based assessments and how video recording and analysis can enable more patient-centric clinical trials!
Developing therapeutics for the treatment of rare diseases usually requires a strong understanding of the natural history of the disease. Often, it also requires the creation of novel assessment tools and clinical trial endpoints. In diseases where mobility is impacted, the use of video to capture the impact of the disease and the assessment of specific parameters, such as gait and stride length, can help design sensitive endpoints. Video as an assessment tool also allows the use of historical videos or videos filmed by non-experts outside of clinical settings. Given the increased use of telemedicine, the use of video may be a useful addition to clinical trial assessments.
Davies, E.H., Matthews, C., Merlet, A. et al. Time to See the Difference: Video Capture for Patient-Centered Clinical Trials. Patient (2022) in conjunction with Alexion, AstraZeneca Rare Disease